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Home » Low Carb

Low Carb Pizza Casserole

Published: Apr 17, 2025 by Angela Coleby · This post may contain affiliate links · This blog generates income via ads ·

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Low Carb Pizza Casserole

Low-Carb Pizza Casserole: A Delicious and Nutritious Twist on Pizza

Are you craving a delicious pizza, but don’t want to deal with the carbs of traditional pizza crust? Look no further! This Low-Carb Pizza Casserole is the answer. It combines all the flavors you love about pizza in a healthy, low-carb format. 

With a combination of ground Italian sausage, melted cheese, and a variety of fresh vegetables, this casserole is not only satisfying but also nutrient-packed. It's a perfect addition to your weekly menu whether you're following a low-carb or keto lifestyle, or simply want to enjoy a healthier pizza alternative without sacrificing taste.

Is this recipe keto-friendly?

Absolutely! This Low-Carb Pizza Casserole is an excellent choice for anyone following a ketogenic diet. The ingredients used in the recipe are all low in carbohydrates, making it a great way to stay within your daily carb limits. Ground Italian sausage provides healthy fats and protein, while the combination of mozzarella and Parmesan cheeses adds richness and creaminess without the carbs. 

The marinara sauce used in the casserole is low-carb, and the vegetables like mushrooms, bell peppers, and olives are full of nutrients but very low in carbohydrates. When combined, these ingredients make a highly nutritious, low-carb meal that is perfect for a keto diet.

Ingredient Breakdown: What Makes Each Ingredient Special

  • Ground Italian Sausage: Packed with flavor, this ingredient forms the base of the casserole. It’s a rich source of protein and healthy fats, which are key components in maintaining energy levels and supporting muscle growth.
  • Shredded Mozzarella Cheese: Mozzarella is the star cheese here, offering that melty, gooey goodness we all love. It’s low in carbs and high in protein and calcium, making it a great choice for anyone looking to maintain a healthy diet.
  • Low-Carb Marinara Sauce: This sauce adds a rich tomato flavor while keeping the carb count low. Tomatoes are high in vitamins and antioxidants, which are beneficial for overall health.
  • Grated Parmesan Cheese: Parmesan adds a sharp, nutty flavor to the casserole and a little goes a long way. It’s also high in protein and calcium, giving the dish an extra boost of nutrition.
  • Sliced Pepperoni: Pepperoni brings a savory, spicy kick to the casserole. While it’s higher in fat, it adds great flavor and is low in carbs, making it a good fit for a low-carb meal.
  • Mushrooms: Mushrooms add an earthy, savory flavor while being low in calories and carbs. They're packed with nutrients like B vitamins, selenium, and antioxidants.
  • Chopped Yellow Bell Pepper: Bell peppers bring a sweet crunch to the casserole, and they are full of vitamin C, which supports immune health.
  • Sliced Black Olives: Olives provide a burst of saltiness and healthy fats, plus they’re rich in antioxidants that help fight inflammation.
  • Diced Red Onion: Red onion adds a slight sweetness and a bit of sharpness to balance the flavors. It also contains antioxidants and fiber, which support digestive health.
  • Dried Italian Seasoning: This blend of herbs brings a classic Italian flavor profile, enhancing the overall taste of the casserole.
  • Olive Oil: Olive oil is an excellent source of healthy fats, which are essential for heart health and maintaining satiety throughout the meal.
  • Salt and Black Pepper: These seasonings bring out all the flavors in the casserole, with black pepper offering a slight kick and salt enhancing the overall taste.

Instructions 

Step 1: Cook the Italian sausage until crumbled and brown. Step 2: Add the meat as a base for the casserole.
Step 3: Add the low-carb tomato sauce.Step 4: Then spread the mozzarella. 
Step 5: Cut the veggies and place them on top of the mozzarella Step 6: Also spread the pepperoni.
Step 7: As the last step, spread the rest of the mozzarella cheese and the parmesan. Preheat the oven at 180°C/360°F and bake the casserole for 20 minutes. 

Cooking Tips: Make the Most of Your Casserole

Cooking this Low-Carb Pizza Casserole is simple, but there are a few tips that can help take it to the next level. First, make sure you’re cooking the sausage thoroughly in a skillet, breaking it into crumbles as it browns. This will ensure the sausage is evenly distributed in the casserole and maximizes the flavor. 

You can also experiment with different types of ground meat such as turkey or chicken sausage if you prefer a leaner option. When it comes to the cheese, feel free to use a blend of mozzarella and other cheeses like provolone or cheddar to add variety. Just remember that using full-fat cheeses will enhance the flavor and make the casserole extra creamy, which is what we want for that irresistible texture.

You can also customize the vegetables according to your preferences. If you’re not a fan of bell peppers, try swapping them for zucchini or spinach. Similarly, swap black olives for green olives or add in some fresh basil for an additional flavor boost.

For a little extra crispiness on top, you can broil the casserole for the last 2–3 minutes of baking to get a golden, bubbly finish.

Try my Spaghetti Squash Pizza Casserole!

Storage Tips: How to Store Your Leftovers

Storing your Low-Carb Pizza Casserole properly is key to keeping it fresh and delicious for days to come. If you have any leftovers, make sure to allow the casserole to cool completely before storing it. This helps prevent excess moisture from forming and keeps the casserole from becoming soggy.

Store the casserole in an airtight container in the refrigerator for up to 3–4 days. When you’re ready to enjoy it again, you can reheat it in the oven at 350°F (175°C) for about 10 minutes to restore its bubbly texture, or in the microwave for a quicker option.

For longer storage, consider freezing the casserole. To freeze, cut it into individual portions and wrap them tightly in plastic wrap or aluminum foil. Then place the wrapped portions in a freezer-safe container or bag. The casserole can be stored in the freezer for up to 3 months. When you're ready to eat, simply thaw it overnight in the refrigerator and reheat in the oven or microwave.

Proper storage ensures that your casserole stays as tasty as when it was first made, and these simple tips will make it easy to enjoy this flavorful meal over multiple days.

Low Carb Pizza Casserole Recipe 

Low Carb Pizza Casserole

Ingredients

  • 1 lb (450 g) ground Italian sausage
  • 2 cups (200 g) shredded mozzarella cheese
  • 1 cup (240 ml) low-carb marinara or pizza sauce
  • ½ cup (50 g) grated Parmesan cheese
  • 1 cup (100 g) sliced pepperoni
  • ½ cup mushrooms 
  • ½ cup (50 g) chopped green bell pepper
  • ½ cup (50 g) sliced black olives
  • ¼ cup (25 g) diced red onion
  • 1 teaspoon dried Italian seasoning
  • 1 tablespoon olive oil
  • Salt and black pepper (to taste)

Instructions

  1. Heat a large skillet over medium heat and add olive oil.
  2. Add the ground Italian sausage and cook, breaking it into crumbles, until browned and fully cooked (about 7–10 minutes).
  3. Preheat your oven to 360°F (180°C).
  4. Spread the cooked sausage evenly across the bottom of a 9x9-inch baking dish.
  5. Pour the marinara sauce over the sausage layer and spread evenly.
  6. Sprinkle half of the shredded mozzarella cheese over the sauce.
  7. Add the green bell pepper, black olives, mushrooms and red onion on top.
  8. Layer the sliced pepperoni over the vegetables.
  9. Sprinkle the remaining mozzarella cheese and parmesan cheese over the top.
  10. Season with Italian seasoning, salt, and black pepper.
  11. Bake in the preheated oven for 20–25 minutes, or until the cheese is bubbly and golden.
  12. Remove from the oven and let it cool for 5 minutes before serving.
Nutrition Facts
Servings: 4
Amount per serving 
Calories461
% Daily Value*
Total Fat 29.3g38%
Saturated Fat 9.5g48%
Cholesterol 125mg42%
Sodium 922mg40%
Total Carbohydrate 5.2g2%
Dietary Fiber 1.2g4%
Total Sugars 2g 
Protein 43.7g48%

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